Salivary Testosterone in Men: Diurnal Variation and Post-Prandial Responses

Exclusion Criteria

• •Subjects with learning disability or those lacking mental capacity to give consent.
• •On (prescribed and over-the-counter) medication and herbal remedies known to affect androgen metabolism.
• •Known hypogonadism.
• •Conditions known to affect androgen metabolism, including chronic inflammatory diseases, chronic liver disease, chronic kidney disease and thyroid dysfunction.
• •Any co-morbidity.
• •Periodontal disease.
• •Dental work 48 hours prior to the test.
• •Exercise on the day, prior to and during sampling periods.
• •Brushed teeth within 1hr prior to sample collection.
• •Obesity defined as a body mass index (BMI) of greater than 29.9 kg/m2As
• •2nd part of study for glucose load - oral glucose tolerance test (OGTT):
• •Subjects with learning disability or lacking mental capacity to give consent.
• •On (prescribed and over-the-counter) medication and herbal remedies known to affect androgen metabolism.
• •Known hypogonadism.
• •Conditions known to affect androgen metabolism, including chronic inflammatory diseases, chronic liver disease, chronic kidney disease and thyroid dysfunction.
• •Subjects with difficult venous access.
• •Periodontal disease.
• •Dental work 48 hours prior to the test.
• •Brushed teeth within 1hour prior to sample collection.
• •Exercise on day prior to and during the OGTT.