Effects of Combined Aerobic and Resistance Training in Patients With Intermittent Claudication

Exclusion Criteria

• •lower-limb ischemic rest pain or gangrene (Fontaine stages III and IV)
• •inability to obtain the ABI value or to perform a walking test
• •exercise tolerance limited by factors other than claudication (i.e., arrhythmias, cardiac symptoms or exaggerated blood pressure rise, severe obesity)
• •end-stage liver or renal failure
• •acute or chronic inflammatory conditions
• •history of recent (\<6 months) acute coronary syndrome, cerebrovascular event or inducible myocardial ischemia
• •treatment with drugs known to affect walking capacity, including calcium-channel blockers, β-blockers and angiotensin-converting enzyme inhibitors.