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Deficit-specific Training in Spinal Disorders | Clinical Trials | Clareo Health

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COMPLETEDNANCT04292717

Deficit-specific Training in Spinal Disorders

Impairments of walking function after spinal cord lesion due to, for example, inflammation, ischemia or trauma are exceptionally diverse. Depending on the size, location and completeness of the spinal...

Lead sponsor: University of Zurich•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

University of Zurich

Collaborators

Swiss National Science Foundation

Age

18 - 80 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Age 18-80 years
•Diagnosis of chronic spinal cord injury (\>6 months cervical or thoracic motor incomplete traumatic or non-traumatic (AIS C, D) above T12 or diagnosis of either primary- progressive, secondary-progressive, or relapsing-remitting multiple sclerosis as defined by the revised McDonald criteria for at least 3 months and with at least one spinal cord lesion as verified in clinical MRI images
•Able to walk without assistance or devices on the treadmill and 10m over ground, but must have impaired walking function as demonstrated by neurological examination.

Exclusion Criteria

•Women who are pregnant or breast feeding
•Current orthopaedic problems of lower limbs
•History of major cardiac condition (e.g., infarction, insufficiency (NYHA II-IV))
•History of major pulmonary condition (e.g., chronic obstructive pulmonary disease GOLD II-IV)
•Current major depression or psychosis
•MS exacerbation within 3 months prior to the screening or at any time during the screening period
•Participation in another training study

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 2, 2025Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment63

Start dateJan 2021

Last updatedDec 2, 2025

Condition

Spinal Cord Injuries Multiple Sclerosis Gait Disorders, Neurologic Training Neurorehabilitation

Locations shown

Universitätsklinik Balgrist

Zurich

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 2, 2025Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions