Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The Ninth Hospital of Nanchang
With
Ascletis Pharmaceuticals Co., Ltd.
Given no specific antiviral therapies for new coronavirus pneumonia approved yet and Ganovo, an oral Hepatitis C virus protease inhibitor, approved in China in June 2018 , this open, controlled trial will evaluate the efficacy and safety of Ganovo in hospitalized patients infected with SARS-CoV-2.
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Aged 18-75 years old;
Pneumonia patients with new coronavirus infection were confirmed to be positive by RT-PCR and clinical manifestations. The diagnosis standard refers to the diagnosis and treatment plan for pneumonia with new coronavirus infection (Current Trial Version);
Patients with newly diagnosed respiratory system discomfort who have been hospitalized (the diagnosis time of respiratory system discomfort shall not exceed 7 days);
Women and their partners who have no planned pregnancy for nearly half a year and are willing to take effective contraceptive measures within 30 days from the first administration of the study drug to the last administration;
Agree not to participate in other clinical research within 30 days from the first administration of the study drug to the last administration;
Patients who voluntarily sign informed consent.
You may not be if
The pneumonia patients with severe new coronavirus infection met one of the following conditions: respiratory distress, RR \>= 30 times / min; or SaO2 / SpO2 \<93% in resting state; or arterial partial pressure of oxygen (PaO2) / concentration of oxygen (FiO2) \<300MMHG (1mmhg = 0.133kpa);
Pneumonia patients with severe new coronavirus infection meet one of the following conditions: respiratory failure and need mechanical ventilation; or shock; or other organ failure combined with ICU monitoring treatment;
Severe liver disease (such as child Pugh score \>=C, AST \> 5 times upper limit);
Patients with contraindications specified in the instructions of ritonavir tablets;
The pregnancy test of female subjects in the screening period was positive;
The researchers judged that it was not suitable to participate in this clinical trial (for example, patients who may be transferred to another hospital during the study period; patients with multiple basic diseases, etc.).
