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UNKNOWNNCT04283916

Botulinum Toxin Injection in the Treatment of Open Abdomen

Botulinum toxin has been widely approved and utilized in the treatment of complex abdominal wall hernias. Botulinum toxin has been only randomly studied in the treatment of open abdomen.

Lead sponsor: University of Oulu•1 locations•View source on ClinicalTrials.gov

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Contacts

Elisa Mäkäräinen-Uhlbäck, M.D.

CONTACT

+358505794011 elisa.makarainen-uhlback@ppshp.fi

Sponsors

Lead Sponsor

University of Oulu

30 consecutive patients who have open abdomen for any indication, will have 300 IU botulinum toxin injected in three spots in either sides of the abdomen within 72 hours of the start of open abdomen. The hypothesis is botulinum toxin relaxes abdominal wall musculature to ensure better and faster closure of the open abdomen.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Open abdomen

Exclusion Criteria

•Previous incisional hernia in midline
•Patient is not in active treatment

Related studies

Active Not RecruitingNA

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Not Yet RecruitingNA

Vacuum Assisted Wound Closure and Permanent On-lay Mesh-mediated Fascial Traction in Patients With Open Abdomen

NCT05568238 · Open Abdomen, Temporary Abdominal Closure, and more

Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction

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COMPLETEDPhase 4

ABRA Abdominal Closure System in Open Abdomen Management

NCT00754156 · Open Abdomen

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: February 1, 2024Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment30

Start dateFeb 2020

Last updatedFeb 1, 2024

Condition

Open Abdomen Botulinum Toxin Injection

Locations shown

Oulu University Hospital

Oulu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 1, 2024Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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