Evaluation Between Surgical Therapy of Lipedema Compared to Complex Physical Decongestive Therapy (CDT) Alone

Exclusion Criteria

• •1. Concurrent lipedema of the arms and legs, in which co-occurrence of lipedema in the arms affects the primary endpoint (i.e., average leg pain), at the discretion of the study investigator
• •2. Previous liposuctions
• •3. Diseases that may limit operability at the discretion of the study physician, e.g. cardiac diseases, coagulation disorders, metabolic diseases, infectious diseases (active), epilepsy; diseases requiring immunosuppression or anticoagulation with medication; allergies to medication accompanying surgery
• •4. Weight \>120.0 kg
• •5. Medical conditions that affect adequate complex decongestive therapy (CDT) at the discretion of the study physician, e.g. heart failure (volume stress), lack of physical ability to wear compression stockings (e.g. joint disease, neurological deficits).
• •6. Primary obesity without disproportion and without evidence of lipedema
• •7. Secondary obesity
• •8. Fat distribution disorders of other genesis (e.g. painless lipohypertrophy, benign symmetric lipomatoses or lipomatosis dolorosa)
• •9. Other edema-causing diseases (such as lymphedema, phlebedema, or myxedema)
• •10. Lack of willingness to ensure adequate contraception
• •11. Positive pregnancy test
• •12. Breastfeeding
• •13. Use of a lymphomat
• •14. Participation in other clinical studies
• •15. Purely cosmetic reasons for participation in the study