A First-in-Human Study of RPT193 in Healthy Volunteers and Patients With Atopic Dermatitis

Exclusion Criteria

• •Parts A \& B (COMPLETED ENROLLMENT):
• •Use of tobacco products within 60 days prior to drug administration
• •History of alcohol abuse or drug addiction
• •Positive drug and alcohol screen
• •Participation in a drug study within 60 days prior to drug administration
• •Donation or loss of more than 100 mL of blood within 60 days prior to drug administration.
• •Donation or loss of more than 1.5 liters of blood (for male subjects) / more than 1.0 liters of blood (for female subjects) in the 10 months prior to drug administration.
• •Part C (COMPLETED ENROLLMENT):
• •Any serious and/or uncontrolled medical condition
• •History of alcohol abuse or drug addiction
• •Positive drug and alcohol screen