Theophylline for Treatment of Pseudohypoparathyroidism

Exclusion Criteria

• •1. History of a seizure disorder unrelated to hypocalcemia
• •2. History of a cardiac arrhythmia (not including bradycardia)
• •3. Hepatic insufficiency including cirrhosis and acute hepatitis (AST or ALT \>3x upper limit of normal)
• •4. Congestive heart failure
• •5. Current cigarette use or alcohol abuse
• •6. Pregnancy or intention to become pregnant during the next year
• •7. Active peptic ulcer disease
• •8. Current use of medications known to effect theophylline levels
• •9. History of hypersensitivity to theophylline or other medication components
• •10. Unable to comply with study procedures in the opinion of the investigator