Development of Predictive Biomarkers for the Diagnosis and Treatment of Asthma and COPD in Vietnam.

Inclusion Criteria

• •Age: ≥ 18 years old
• •Signed informed consent
• •Out-patients at Nguyen Tri Phuong Hospital
• •One or several symptoms suggesting chronic respiratory disease (cough, chest tightness, wheezing, dyspnea or sputum), lasting 3 months or more.
• •Lung function abnormality (Forced Expiratory Volume in 1 Second /Forced Vital Capacity \< Lower Limit of Normal)
• •Patients are able to stop anti-histamine 5 days before evaluation
• •Patients are able to stop bronchodilator treatment before performing lung function test according to standard practice (immediate release theophylline: 24 hours, long acting β2-agonist: 12 hours, short acting β2-agonist: 6 hours and short acting anticholinergic: 8 hours).