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A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base | Clinical Trials | Clareo Health

COMPLETEDNA

A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base

NCT04218591•Karolinska Institutet

View on ClinicalTrials.gov

Summary

Randomized comparison between Platelet Rich Plasma (PRP) and placebo (Saline) for thumb base.osteoarthritis.

Eligibility

Age

All ages

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Arthritis in the thumb base.
•Radiological Eaton Littler class 1-3.
•Clinical signs of thumb base osteoarthritis: pain at palpation of the CMC-1 joint and pain during provocation/grinding test.

Exclusion Criteria

•Rheumatoid arthritis.
•Ongoing infection in the hand or wrist.
•History of gout or pseudo gout.
•Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).
•Intra-articular injection in the affected joint within 6 months.
•Eaton Littler class 4 (STT joint involved).

Locations (1)

Department of Hand Surgery Södersjukhuset

Stockholm, Sweden

Key Dates

Start Date

February 24, 2020

Primary Completion Date

December 31, 2023

Completion Date

December 31, 2023

Last Updated

January 19, 2024

Enrollment

ACTUAL participants

Conditions

Thumb Osteoarthritis

Interventions

PRP

OTHER

Placebo

OTHER

ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Model

NCT07458971

Trapeziometacarpal OsteoarthritisThumb Osteoarthritis+2 more

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COMPLETEDPHASE3

Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis

NCT07171840

Thumb Osteoarthritis

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 19, 2024Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base

Inclusion Criteria

Exclusion Criteria

ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Model

Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthritis

Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment

Effectiveness of Proprioceptive Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis

Autologous Stromal Vascular Fraction in the Treatment of Thumb Basal Joint Osteoarthritis

Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthritis