Duke Spine Outcome Study (DSOS)

Exclusion Criteria

• •History of substance abuse (recreational drugs, alcohol) within 12 months prior to screening
• •Is a prisoner.
• •A disease or condition that would, in opinion of the investigator, preclude accurate evaluation
• •(e.g. significant psychiatric disease), or that would impair the ability of the patient to receive protocol treatment or comply with protocol.
• •Pregnant or breast feeding during the study period (women of child-bearing potential will require a negative serum pregnancy test within 30 days of enrollment).
• •Active infection, or fever of unknown origin.
• •Inflammatory bowel disease.
• •Systemic lupus erythematosus.
• •Rheumatoid arthritis, or other autoimmune disease.
• •History of or active hematologic or bone marrow diseases, including but not limited to diagnosed lymphomas, leukemias, sickle cell or other anemias not associated with their current condition.
• •Polycythemia vera.
• •Known or suspected immunodeficiency or Human Immunodeficiency Virus (HIV).
• •Hematocrit \< 24% pre-operatively.