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COMPLETEDNCT04203212

BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH

The investigators aim to investigate the effect of menstrual cessation in women with endometriosis treated with GnRH analogs for 6 months on bone mineral density and bone and muscle metabolism paramet...

Lead sponsor: 424 General Military Hospital•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

424 General Military Hospital

Collaborators

251 Hellenic Air Force & VA General Hospital
Aristotle University Of Thessaloniki

Prospective, open-label, controlled 12month observational study Premenopausal women with surgically verified endometriosis will receive goserelin 1 injection per month for 6 months. Subsequently goserelin will be discontinued and patients will be monitored for another 6 months after menstrual restoration. Age- and BMI-matched premenopausal, health women will serve as controls. Controls will receive no treatment.

Age

18 - 45 years

Sex

FEMALE

Healthy Volunteers

Yes

Inclusion Criteria

•Premenopausal women with surgically verified endometriosis

Exclusion Criteria

•1. Secondary osteoporosis
•2. diseases or conditions that could affect bone and/or muscle metabolism
•3. any medications that could affect bone and/or muscle metabolism

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 12, 2021Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment41

Start dateOct 2019

Last updatedJan 12, 2021

Condition

Endometriosis Bone Density Muscle Bone Metabolism

Locations shown

424 General Military Hospital

Thessaloniki

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 12, 2021Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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