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Oxygen Titration Protocol for Exertion of COPD Patients by an Automated Adjustment Device: a Monocentric, Prospective, Cross-over Study.
The aim of our study is to assess if an automated titration of oxygen flow during exertion can be a useful tool to determinate the level of oxygen required by COPD patients that are using oxygen therapy during exercise.
All patients referred to our centre of oxygen titration during exertion will be offered to participate in our study. After baseline assessments, patients will have an oxygen titration using two different methods in random order: * Usual titration protocol will include an manual oxygen increase during a titration 6 minutes walk test * Automatic titration protocol that will use the automated oxygen titration device to adjust oxygen flow rate during a titration 6 minutes walk test. After each titration protocol, the efficacy of the titration will be assessed in 3 validation 6 minutes walk tests during which oxygen flow will be set at: * The manually determined flow rate * The 95th percentile flow rate of the automatic titration * The median flow rate of the automatic titration During validation 6 minutes walk test, oxygen saturation, dyspnea, walked distance and heart rate will be recorded.
Age
18 - 85 years
Sex
ALL
Healthy Volunteers
No
CHU Charles Nicolle
Rouen, France
Start Date
February 6, 2020
Primary Completion Date
December 1, 2023
Completion Date
December 1, 2023
Last Updated
November 15, 2023
25
ESTIMATED participants
Free 02
DEVICE
Lead Sponsor
ADIR Association
NCT07477600
NCT07462221
NCT07351929
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