Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation

Inclusion Criteria

• •1. Age ≥18.0 years old at time of consent
• •2. History of insulin requiring diabetes mellitus, type 1 or type 2, who have end stage renal disease (ESRD)
• •3. Expected to undergo deceased or living donor kidney transplant surgery
• •4. History of insulin prescription (past or current use)
• •5. If female and sexually active, must agree to use a form of contraception to prevent pregnancy while a participant in the study. A negative serum or urine pregnancy test will be required for all females of childbearing potential. Participants who become pregnant will be discontinued from the study.
• •6. Willingness to switch to lispro (Humalog) or aspart (Novolog) if not using already, and to use no other insulin besides lispro (Humalog) or aspart (Novolog) during the study
• •7. Total daily insulin dose (TDD) at least 10 U/day
• •8. An understanding and willingness to follow the protocol and signed informed consent