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The Effect of Hydroxyzine and Alprazolam Premedication on Preoperative Anxiety and Patient Satisfaction
Patients will be divided into three groups. Group H patients will be given 100 mg Hydroxyzine orally 1 hour before surgery while group A patients will receive 0.5 mg Alprazolam orally. group P will be placebo group. Amsterdam Preoperative Anxiety and Knowledge Scale (APAIS) anxiety scores will be evaluated and recorded 1 hour before surgery. APAIS score will be evaluated again in the the operation room before surgery started. After base measurements of patients are recorded with standard monitoring, spinal block will be performed with 15 mg Heavy Bupivacaine from the L2-L3 or L3-L4 levels of spinal cord in sting position. When T10 level sensory block and Bromage 0-1 neuromusculer block will be occured , surgery will be started. Heart rate, non-invasive arterial blood pressure and the degree of peripheral O2 saturation will be measured at 5 minutes interval throughout the operation. IOWA anesthesia satisfaction scale will also performed to the patients the day after the surgery.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
No
Start Date
December 1, 2019
Primary Completion Date
June 1, 2020
Completion Date
September 1, 2020
Last Updated
December 6, 2019
90
ESTIMATED participants
Hydroxyzine Hydrochloride
DRUG
Alprazolam tablet
DRUG
Placebo
DRUG
Lead Sponsor
Istanbul Medeniyet University
Data Source & Attribution
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