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UNKNOWNNCT04159337

NGS-based Large-panel in Targeted Drug Delivery and Immunotherapy of Lung Cancer

Companion diagnosis by large-panel is in increasing acceptance and need during clinical cancer management. The purpose of this trial is to investigate the benefit of large-panel NGS analysis in compan...

Lead sponsor: Shanghai Chest Hospital•1 locations•View source on ClinicalTrials.gov

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Contacts

Niu Xiaomin

CONTACT

021-22200000-3403 ar_tey@hotmail.com

Sponsors

Lead Sponsor

Shanghai Chest Hospital

Fresh tumor tissues and matched blood cells will be analyzed by large-panel (Berryoncology, lnc.) for multiple molecular biomarkers including mutations with sensitivity/resistance to targeted therapies, tumor mutational burden (TMB), microsatellite instability (MSI) status, etc., Therapeutic approach and outcome will be followed-up to inspect the clinical benefit by large-panel analysis. In addition, selected samples will be analyzed by WES to assess the correctness of TMB estimated by large-panel.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participant aged 18 or above, and gender unrestricted
•Individual with pathologically diagnosed lung cancer

Exclusion Criteria

•Patients with concomitant other tumors
•Individual with severe cardiopulmonary insufficiency and hypoproteinemia
•Women who were pregnant and were during their lactation

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 12, 2019Terms

Trial snapshot

StatusUNKNOWN

Phase—

Enrollment2,000

Start dateAug 2019

Last updatedNov 12, 2019

Condition

Locations shown

Shanghai Chest Hospital

Shanghai, Shanghai Municipality

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 12, 2019Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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