Alternating Urine Redox Status Of Consecutive Menstrual Cycles

Exclusion Criteria

• •1\. Subject is pregnant, or trying to or planning to become pregnant during the study.
• •2\. Subject was pregnant within 1 year of beginning study, regardless of the outcome of pregnancy.
• •3\. Subject who is breastfeeding. 4. Subject who is not menstruating for any reason or plans to undergo or change circumstances that might affect menstruation (e.g., certain athletic training regimens, significant dietary changes).
• •5\. History of recent or current irregular menstrual cycles (as self-reported by the subject).
• •6\. Subject reports she has been told by a medical professional that she is not ovulating (i.e., has anovulatory periods) at any time during the previous 12 months.
• •7\. Subject is using or planning to use any method to regulate her periods. 8. Subject smokes (includes tobacco and marijuana) or vapes. 9. By history, subject has medical problems that might influence the results of the study, such as endocrinologic, renal, or hormonal problems.
• •10\. Known polycystic ovarian syndrome (by history). 11. Subject is taking or planning to take hormones or hormone- enhancing/manipulating pharmaceuticals (including "morning after pill" \[levonorgestrel\], birth control pills, Clomid \[clomiphene citrate\], Femara \[letrozole\], Cialis \[tadalafil\]\*, Viagra \[sildenafil\]\* and similar medications) and/or agents to influence hormonal status such as herbal products or nutritional supplements. (\*Not approved for use and should be avoided by women.) 12. Subject is using or planning to use hormonal contraceptives of any type, including oral contraceptives and intrauterine devices.
• •13\. Subject is using or planning to use hormonal therapies for acne vulgaris or other conditions, including spironolactone, flutamide, metformin, or oral contraceptives used as acne therapies, including Ortho Tri-Cyclen (combination of norgestimate and ethinyl estradiol \[EE\]), Estrostep (combination of norethindrone acetate and EE), and Yaz/Yasmin (combination of drospirenone and EE).
• •14\. Subject is using or planning to use estrogen products, including topicals/creams, for any purpose.
• •15\. Subject is using or planning to use androgens or anabolic steroids (e.g., stanazolol/danazol) for any reason, including for training or athletic purposes..
• •16\. Subject has attempted or taken IVF or IUI treatment within the prior six months.
• •17\. Subject has uncontrolled diabetes or other significant medical disorder that might, in the investigator's opinion, preclude completion of the study or suggest that an exclusion criterion will ensue.
• •18\. Subject reports difficulty handling biologic fluids, specifically urine, or gives other reasons why she is hesitant to participate.