Physical or intellectual impairment precluding informed consent or protocol adherence

Non-German speaking (precluding informed consent)

Acute or recent (within the last 6 weeks) exacerbation of COPD

Attending a pulmonary rehabilitation program within the last 3 months

Pregnant patients

History of thromboembolic event in the lower extremity

Diagnosis of polyneuropathy

Resting systolic blood pressure \<100 mmHg

Low-load Blood Flow Restriction Training in COPD