PREMIER: PREvention of Metabolic Illness Through prEcision nutRition

Exclusion Criteria

• •Willing to comply with the study intervention.
• •Able to provide informed consent
• •Refuse or are unable to give informed consent to participate in the study.
• •Have type I or type II diabetes mellitus or are taking medications for type II diabetes mellitus. Those not on medications but having a capillary glucose level of \>126 mg/dL based on fingertip glucose measurements will be excluded.
• •Are obese (BMI\>30.0kg/m2) or underweight (BMI\<18.5kg/m2).
• •Have had a heart attack (myocardial infarction) or stroke
• •Have had cancer in the last 3 years, excluding skin cancer.
• •Have an ongoing inflammatory disease i.e. Rheumatoid arthritis, systemic lupus erythematosus, polymyalgia and other connective tissue diseases.
• •History of cirrhosis and/or aspartate aminotransferase (AST) or alanine aminotransferase (ALT) more than 3 times the upper limit of normal (ULN).
• •Are currently suffering from acute clinically diagnosed depression.
• •Currently taking or intending to take during the study duration any medication known to affect glycemic parameters, such as glucocorticoids or fluoroquinolones.
• •Are unable to fast from 9pm the night before the clinic visit until 9am on the clinic day
• •Are pregnant or breastfeeding.
• •Are participating in another clinical study.
• •Are vegan, suffering from an eating disorder or unwilling to eat foods that are part of the study.