A Study of Armed, Activated T-Cells in Patients With Advanced Pancreatic Cancer

Exclusion Criteria

• •Any chemotherapy related toxicities from prior treatment, \> grade 2 per CTCAE v4.0
• •Known hypersensitivity to cetuximab or other EGFR antibody
• •Treatment with any investigational agent within 14 days prior to being registered for protocol therapy
• •Symptomatic brain metastasis
• •Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy or any other form of immunosuppressive therapy within 7 days prior to the first dose of trial treatment. Steroid premedication for imaging scans is allowed. Replacement therapy (eg., thyroxine, insulin, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment.
• •Serious non-healing wound, ulcer, bone fracture, major surgical procedure, open biopsy or significant traumatic injury within 28 days prior to being registered for protocol therapy
• •Active liver disease such as cirrhosis, chronic active hepatitis or chronic persistent hepatitis
• •Known HIV infection
• •Active bleeding or a pathological condition that is associated with a high risk of bleeding (therapeutic anticoagulation is allowed)
• •Has an active infection requiring systemic therapy
• •A serious uncontrolled medical disorder that in the opinion of the Investigator may be jeopardized by the treatment with protocol therapy.
• •Females must not be breastfeeding
• •Patient may be excluded if, in the opinion of the PI and investigator team, the patient is not capable of being compliant