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Ketamine for Acute Pain Management After Trauma | Clinical Trials | Clareo Health

COMPLETEDPHASE4

Ketamine for Acute Pain Management After Trauma

Ketamine for Acute Pain After Trauma: KAPT Trial

NCT04129086•The University of Texas Health Science Center, Houston

Summary

The purpose of this study is to compare the effectiveness of Ketamine drip along with usual care and usual care alone on trauma patients and to longitudinally quantify the pain experience of patients during hospitalization.

Eligibility

Age

16 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Adult trauma patients
•Admission to Shock Trauma ICU (STICU) or Surgical Intermediate Unit (SIMU)
•Randomization within 6 hours of arrival

Exclusion Criteria

•Patient not expected to survive
•Contraindications to ketamine Allergy, Poorly controlled hypertension, Cardiac arrhythmia disorders (including atrial fibrillation), congestive heart failure, unstable coronary artery disease or recent myocardial infarction( MI)(within 6 months), cirrhosis, seizure disorder, and for those patients with unknown medical history - median sternotomy scar, mechanism of injury is fall from standing, 65 years of age or older, any arrhythmia on EKD)
•pregnancy
•in police custody
•history of dementia or movement disorder (i.e. Parkinson's)

Locations (1)

The University of Texas Health Science Center at Houston

Houston, Texas, United States

Key Dates

Start Date

July 1, 2020

Primary Completion Date

March 30, 2022

Completion Date

September 30, 2022

Last Updated

April 21, 2023

Enrollment

305

ACTUAL participants

Conditions

Trauma InjuryPainOpioid Use

Interventions

Ketamine plus usual care

DRUG

Usual Care

DRUG

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RECRUITINGPHASE1

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 21, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Ketamine for Acute Pain Management After Trauma

Inclusion Criteria

Exclusion Criteria

Effect of Virtual Reality on Patient's Comfort During Cardiac Electronic Device Implantation.

A Phase Ib Study to Evaluate the Efficacy and Safety of HRS-2129 in Patients With Knee Osteoarthritis

Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy

Intertransverse Process Block to Improve Quality of Recovery and Pain Management in Adult Cardiac Surgical Patients

Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination

PENG Block Variants With Dexamethasone and Dexmedetomidine in Older Adults