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The Prevalence of Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery
Morbidly obese patients are at risk for diastolic cardiac dysfunction, which can lead to adverse event, such as, diastolic heart failure postoperatively. Preoperative screening by transthoracic echocardiogram is difficult due to anatomical challenge, therefore the prevalence of this problem may be underestimated. The investigator would like to perform transesophageal echocardiogram in this group of patients after anesthesia induction to demonstrate the true prevalence of this syndrome.
Morbidly obese patients are at risk for both respiratory and cardiovascular abnormalities. Many cardiac problems were previously reported including left ventricular hypertrophy, right and left ventricular systolic dysfunction etc. Diastolic cardiac dysfunction can be found in normal left ventricular systolic function and can lead to diastolic heart failure postoperatively. Preoperative screening by transthoracic echocardiogram is difficult due to anatomical challenge (thick chest wall, narrowing of inter-rib space), therefore the prevalence of this problem may be underestimated. Transesophageal echocardiogram provides better cardiac view, but requires sedation during procedure. So, it is not practical for out-patient setting. The investigator would like to perform transesophageal echocardiogram in this group of patients after anesthesia induction to demonstrate the true prevalence of this syndrome.
Age
18 - 70 years
Sex
ALL
Healthy Volunteers
No
Faculty of Medicine Siriraj Hospital
Bangkok, Thailand
Start Date
October 30, 2019
Primary Completion Date
December 30, 2022
Completion Date
February 28, 2023
Last Updated
March 16, 2023
116
ACTUAL participants
Lead Sponsor
Mahidol University
NCT07480265
NCT05783466
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT06431919