Low-moderate Intensity Pedaling During Immunotherapy Administration

Exclusion Criteria

• •ECOG Performance Status of Grade 3-5
• •Severe cardiac history or comorbidities (i.e. heart failure, clinically significant aortic stenosis, history of cardiac arrest, have a cardiac defibrillator, uncontrolled angina, uncontrolled arrhythmias, major heart surgery, stroke, or pulmonary embolus).
• •Chest pain or severe shortness of breath at rest or with physical activity.
• •Orthopedic impediments to exercise (i.e. joint immobility or lower extremity lymphedema).
• •Limitations to sustained exercise (i.e. bone metastases in the femur neck).
• •Severe arthritis (i.e. osteoarthritis or rheumatoid arthritis).
• •Patients will be excluded from study if their immunotherapy treatment requires the use of sedating antihistamines prior to treatment.