Laboratory test values must meet the following standards within 7 days before enrollment;
Women of reproductive age must confirm that the serum pregnancy test is negative and agree to use effective contraceptive measures during the study drug use
You may not be if
Uncontrolled or symptomatic hypercalcemia;
Had major surgery or had not fully recovered from previous surgery within 4 weeks before enrollment;
central nervous system(CNS) metastases;
Bone metastases;
Uncontrolled pleural effusion, pericardial effusion, or ascites requiring repeated drainage (once a month or more frequently) allow the patient to have a catheter indwelling;
Having a history of idiopathic pulmonary fibrosis, organic pneumonia;
Uncontrolled active infection, including but not limited to acute pneumonia;
Have other malignant tumors at the same time;
The patient has any active autoimmune diseases or a history of autoimmune diseases;
Liver diseases of known clinical significance, including active viral viral hepatitis, alcoholic hepatitis or other hepatitis, cirrhosis, fatty liver and hereditary liver diseases.
Previous use of anti-PD-1 antibody, anti-PD-l1 antibody, anti-PD-l2 antibody or anti-CTLA-4 antibody;
Patients with active tuberculosis (TB);
Received systemic immunosuppressive within 4 weeks prior to day 1 of the first cycle;
Pregnancy test positive;
Known human immunodeficiency virus (HIV) infection;
A history of severe allergy, anaphylaxis or other hypersensitivity reactions to chimeric or humanized antibodies or fusion proteins;
Those who are known to be allergic to biological drugs produced by hamster ovary cells in China, or to citric acid monohydrate, sodium citrate dihydrate, mannitol and polysorbate (components of the experimental drugs);
Patients who have previously received allogeneic stem cells or parenchymal organ transplantation.
