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Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery:A Prospective Randomized Clinical Trial
This study was conducted to evaluate clinical and radiographical outcome of using a standardized platelet-rich plasma (PRP) biomembrane following endodontic surgery and its correlation with the growth factors content in this concentrate.
15 healthy patients of both genders, between 20 and 45 years of age, presenting with 22 anterior/premolar teeth in need of endodontic surgery were recruited. Teeth presented with failed non-surgical root canal therapy and periapical radiolucency of ≥ 1cm in size. Patients were randomly divided following surgery into two groups, with 11 teeth each.
Age
20 - 45 years
Sex
ALL
Healthy Volunteers
No
faculty of dentistry, Alexandria University
Alexandria, Egypt
Start Date
November 24, 2014
Primary Completion Date
September 12, 2017
Completion Date
October 12, 2017
Last Updated
September 30, 2019
15
ACTUAL participants
osteotomy filled with PRP-gel and covered with PRP-biomembrane
PROCEDURE
osteotomy site following the surgical intervention was left empty
PROCEDURE
Lead Sponsor
Alexandria University
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT04527705