Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery

Inclusion Criteria

• •1. Healthy patients.
• •2. Selected tooth with previous root canal therapy failure and in need of endodontic surgery.
• •3. Existence of a periapical radiographic lesion surrounding the root canal treated tooth, of size ≥ 1 cm.
• •4. Healthy periodontal condition (probing depth, mobility \& epithelial attachment level are all within normal range).