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Volatile Anaesthesia and Perioperative Outcomes Related to Cancer (VAPOR-C): A Feasibility Study
A multicentre, prospective randomized, active-controlled feasibility trial of volatile-based anaesthesia vs. propofol-based total intravenous anaesthesia to investigate the impact of anaesthesia on long-term (i.e. 5-years) patient cancer outcomes in patients undergoing elective major cancer surgery.
This study aims to assess the feasibility of conducting a phase IV, multi-centre, single-blinded, randomized control trial (VAPOR-C (Main)). Primary aims To measure the ability to recruit eligible patients into the study. To measure the ability to successfully deliver each of the two anaesthetic techniques (volatile-based general anaesthesia and propofol-based anaesthesia) according to the research protocol.
Age
18 - 80 years
Sex
ALL
Healthy Volunteers
No
Peter MacCallum Cancer Centre
Melbourne, Australia
Start Date
August 27, 2017
Primary Completion Date
October 31, 2019
Completion Date
June 30, 2020
Last Updated
June 9, 2022
169
ACTUAL participants
Propofol
DRUG
isoflurane, sevoflurane or desflurane
DRUG
Lead Sponsor
Peter MacCallum Cancer Centre, Australia
Collaborators
NCT05577143
NCT07268846
NCT03451383
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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