* Use of another hyperkalemic diuretic or potassium salts
* Renal insufficiency (clearance \<60 ml / min)
* Severe hepatocellular insufficiency
* In combination with lithium, converting enzyme inhibitors, angiotensin II inhibitors (except if there is hypokalemia), ciclosporin, tacrolimus, non-antiarrhythmic drugs giving torsades de pointes
Cardiovascular and renal history, for subjects over 75 years old
Patient, who from an investigator's point of view would not be compliant to the procedure of the study
Pregnant or lactating patient
Patient under trusteeship, under guardianship, protected by law
