Phase I: Short survey of lead clinicians of familial cancer services, descriptive analysis of recommendations by areas of the country
Phase II: Prescribing data analysis (using OpenPrescribing) comprising:
1. t-test to compare the chemoprevention prescribing rate in general practices where chemoprevention is recommended versus not recommended;
2. interrupted times series analysis to assess the change in the chemoprevention prescribing after recommendation from specialist compared with changes occurring in practices where chemoprevention is not recommended and
3. panel regression across all practices, in order to distinguish the relative impacts of national versus local recommendation, and the change over time.