previously received at least one systemic treatment (including chemotherapy) without remission or relapse after remission;
at least one evaluable lesion；
ECOG PS 0-1;
18-65 years;
proper functioning of the major organs.
You may not be if
involvement of central nervous system;
with other malignancy;
patients receiving or received drug of other clinical trial within 30 days；
previously received doxorubicin liposome or have used other anthracycline drug with accumulated restricted doses (adriamycin 450mg/m2, epirubicin 935mg/m2, acrarubicin 900mg/m2)；
patients who received treatment for hematologic toxicity caused by previous chemotherapy within 7 days before enrollment;
