Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
University of Massachusetts, Amherst
The purpose of this study is to assess the efficacy of supplementation with tetrahydrobiopterin (BH4) for improving vascular and muscle function in patients with COPD and healthy controls.
Age
18–85
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
All subjects must be between the age of 18 and 85 years;
For the COPD cohort, patients with a diagnosis of stable COPD (i.e., those not experiencing an acute exacerbation of symptoms) and spirometric evidence of airway obstruction (FEV1 \<80% predicted, FEV/FVC\<0.70);
Ability to perform motor tests;
Ability to provide informed consent
You may not be if
uncontrolled hypertension;
hyperlipidemia;
recent exacerbation;
Major cardiovascular event procedure (\<3 months);
Pregnancy
known significant hepatic, renal disease, active substance abuse
contraindication to MRI, claustrophobia
Clareo Health | O2 Transport and Utilization in Health and Lung Disease
