Diphtheria Vaccination in Adolescents With Inflammatory Bowel Disease

Immunogenicity of Diphtheria Booster Vaccination in Adolescents With Inflammatory Bowel Disease

NCT03998215•Medical University of Warsaw

Summary

Assessment of the immunogenicity and safety of booster immunization against diphtheria in children with inflammatory bowel disease.

Eligibility

Age

11 - 18 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•diagnosis of Crohn's disease or ulcerative colitis based on standard clinical, endoscopic, histologic and radiographic criteria (Porto criteria),
•vaccination, as a part of the basic vaccination course, with five doses of diphtheria, tetanus and whole-cell pertussis vaccine, without booster dose after the age of 6,
•written consent of the patient's legal guardians and the patient himself if he/she turns 16 years of age.

Exclusion Criteria

•serious exacerbation of inflammatory bowel disease defined as Paediatric Ulcerative Colitis Activity Index (PUCAI) \> 65 points for patients with ulcerative colitis or Pediatric Crohn's Disease Activity Index (PCDAI) \> 40 points for patients with Crohn's disease.

Key Dates

Start Date

December 1, 2012

Primary Completion Date

January 1, 2015

Completion Date

January 1, 2015

Last Updated

June 26, 2019

Enrollment

ACTUAL participants

Conditions

DiphtheriaInflammatory Bowel Diseases

Interventions

Diphtheria booster vaccination

BIOLOGICAL

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883

Inflammatory Bowel DiseasesCrohn's Disease

View study

RECRUITING

Institutional Registry of Rare Diseases

NCT06573723

Rare DiseasesAmyloidosis+24 more

View study

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 26, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

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Diphtheria Vaccination in Adolescents With Inflammatory Bowel Disease

Inclusion Criteria

Exclusion Criteria

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Institutional Registry of Rare Diseases

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Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study

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Clinnova-IBD, a Prospective Cohort of Patients With Inflammatory Bowel Disease (IBD)