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TERMINATEDNANCT03998189

Metabolic and Microbial Profiling of Lung Cancer

This pilot study will establish non-invasive sample collections, including breath, saliva, blood and urine pre-surgery and at the participant's one-month post-surgery follow-up visit. Participants wit...

Lead sponsor: Wake Forest University Health Sciences•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Wake Forest University Health Sciences

Collaborators

National Cancer Institute (NCI)

Primary Objective * To evaluate the feasibility of adding non-invasive sample collections in the pre-surgical setting and at the post-surgery follow-up visit. * To identify and assess metabolic and microbial signatures collected at pre- and post-surgery and determine which are indicative of lung cancer. Secondary Objective * To identify signatures which are associated with lung cancer stage. * To identify signatures which are impacted by patient's pulmonary function status.

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Male and female patients age \>18 years, of all racial and ethnic origins, with suspected nonsmall cell lung cancer stages I, II, and III, as evident through radiographic evidence and felt acceptable to undergo surgical resection.
•Patients who have the ability to understand and the willingness to sign a written consent form.

Exclusion Criteria

•Patients who are have taken antibiotics within two weeks.
•Patients who are on continuous supplemental oxygen.
•Patients currently undergoing active treatment for other malignancies.
•Subjects who are unable or unwilling to provide consent.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: November 5, 2021Terms

Trial snapshot

StatusTERMINATED

PhaseNA

Enrollment1

Start dateOct 2019

Last updatedNov 5, 2021

Condition

Nonsmall Cell Lung Cancer Nonsmall Cell Lung Cancer Stage

Locations shown

Wake Forest Baptist Comprehensive Cancer Center

Winston-Salem, North Carolina

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: November 5, 2021Data synced to Clareo: June 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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