Loading clinical trials...
Loading clinical trials...
To Characterize Tumor Hypoxia by Magnetic Resonance Imaging in African American and Caucasian Prostate Cancer Patients
The purpose of this research study is to measure the hypoxia (low oxygen condition) in prostate cancers and its effect in survival. In this study, investigators will assess hypoxia by magnetic resonance imaging (MRI) and create a hypoxia score. Investigators will study the hypoxia score and how it correlates (if any) to the disease aggressiveness as well as its effect on the treatment outcomes.
Primary Objective(s): * To assess hypoxia in primary prostate tumors by magnetic resonance imaging. * To correlate hypoxic score with disease aggressiveness (proliferation biomarkers' expression). Secondary Objective(s): * To correlate hypoxic score with ExoHypoxic concentration in plasma of same patient. * To correlate hypoxic score with fatty acid synthase (FASN) expression.
Age
40 - No limit years
Sex
MALE
Healthy Volunteers
No
Start Date
July 10, 2019
Primary Completion Date
November 15, 2021
Completion Date
November 15, 2021
Last Updated
December 21, 2022
Blood draws
OTHER
Magnetic resonance imaging (MRI)
DIAGNOSTIC_TEST
Lead Sponsor
Wake Forest University Health Sciences
Collaborators
NCT04550494
NCT06842498
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT05691465