Serum Neurofilament-light Chain and GFAP Levels in Patients From the OFSEP Cohort at Different Landmarks of Multiple Sclerosis

Inclusion Criteria

• •The patient has been correctly informed.
• •The patient must have given their informed and signed consent.
• •The patient must be insured or beneficiary of a health insurance plan.
• •The patient is at least (≥)15 years old.
• •The patient has MS according to diagnosis criteria (Thompson et al. 2017) and:
• •* Participates to the OFSEP-HD cohort (ancillary study);
• •* Has a Expanded Disability Status Scale score comprised between 0 - 7.0;
• •* With or without Disease Modifying Drug;
• •* For Work Package 3: patients enrolled in any OFSEP-HD centre that meet landmark criteria for an active MS (relapse, or Expanded Disability Status Scale progression, or active MRI) during follow-up;
• •* For Work Package 4: patients with a stable disease enrolled in OFSEP-HD study in Nîmes or Nantes University Hospitals.