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Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome | Clinical Trials | Clareo Health

UNKNOWN

Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome

Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome: a Cross-sectional Study

NCT03965442•Hospital de Base

Summary

Chronic postoperative pain is an entity that is usually neglected by anesthetists, but several studies show that the choice of anesthetic technique may interfere with this prevalence. Esmolol is a selective beta-blocker of ultra fast duration that has been studied as a perioperative venous adjuvant with antihyperalgesic and opioid sparing action. The investigators ventured the possibility of this anti-hyperalgesic effect attenuating the chronic pain syndrome post-mastectomy.

Eligibility

Age

18 - 65 years

Sex

FEMALE

Healthy Volunteers

Inclusion Criteria

•\- Patients previously submitted to the study Analgesic Effect of Intraoperative Esmolol in Mastectomies: a randomized placebo controlled trial

Exclusion Criteria

•Patient aged less than 18 years and over 65 years;
•Patients who refuse to participate in the study;
•Patients with pulmonary disease;
•Patients with cardiac, renal or hepatic disease;
•Use of psychoactive drug;
•Patients with sinus bradycardia;
•Pregnant women;
•Patients with allergy to dipyrone, morphine;
•Patients with chronic pain prior to the surgical procedure;
•Patients with neurological disorders;
+1 more criteria

Locations (1)

Hospital de Base do Distrito Federal

Brasília, Federal District, Brazil

Key Dates

Start Date

January 1, 2019

Primary Completion Date

July 31, 2019

Completion Date

July 31, 2019

Last Updated

May 29, 2019

Enrollment

ESTIMATED participants

Conditions

Post-mastectomy Pain Syndrome

Interventions

Control

DRUG

Esmolol

DRUG

Contacts

Fabricio T Mendonça, MD

CONTACT

+5561981882640 correidofabricio@gmail.com

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 29, 2019Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effects of Intraoperative Esmolol on Post-mastectomy Pain Syndrome

Inclusion Criteria

Exclusion Criteria

Chronic Pain in Post-Mastectomy Patients; The Difference Between Pectoral Nerve (PECS I-II) and Erector Spinal Plane (ESP) Blocks

Stellate Ganglion Destruction With Alcohol Versus Thermal Ablation for Chronic Post Mastectomy Pain

Evaluation and Re-evaluation of Post-mastectomy Pain Syndrome by Breast Cancer EDGE Task Force Outcomes

Perioperative Pregabalin and Lidocaine to Reduce Chronic Breast Cancer Pain