TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection

Exclusion Criteria

• •* History or hypersensitivity or intolerability to any fluoroquinolone, rifamycin or glycopeptide classes;
• •* ABSSSI suspected or confirmed to be caused by pathogens that are resistant to the glycopeptide class;
• •* Prior administration of systemic antibacterial therapy within 96 hours before randomization;
• •* ABSSSI with suspected or confirmed infection caused by gram-negative or anaerobic organisms;
• •* ABSSSI with suspected or confirmed infection caused by fungal, mycobacterial, parasitic, or viral pathogens;
• •* Evidence of significant hepatic, hematologic, or immunologic disease;
• •* History or evidence of severe renal disease.