Lead Sponsor

Eli Lilly and Company

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Participants with migraine with or without aura fulfilling the International Classification of Headache Disorders (ICHD)-2.
•History of disabling migraine for at least 1 year.
•Migraine Disability Assessment Test (MIDAS) score ≥11.
•Migraine onset before the age of 50 years.
•History of 3-8 migraine attacks per month and \<15 headache days per month during the past 3 months.

•Known hypersensitivity to lasmiditan, or to any excipient of lasmiditan oral tablets.
•History or evidence of hemorrhagic stroke, epilepsy, or any other condition placing the patient at increased risk of seizures.
•History of recurrent dizziness and/or vertigo including benign paroxysmal positional vertigo, Meniere's disease, vestibular migraine, and other vestibular disorders.
•History of diabetes mellitus with complications (diabetic retinopathy, nephropathy, or neuropathy).
•History of orthostatic hypotension with syncope.