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Deep Brain Stimulation for Alzheimer's Disease

NCT03959124·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Shin-Yuan Chen, MD.
CONTACT
+886-3-8561825 william.sychen@msa.hinet.net
Ting-Wen Hou, BS.
CONTACT
+886-3-8561825 tcpdcenter@gmail.com

Lead

Buddhist Tzu Chi General Hospital

With

Beijing Tiantan Hospital

Age

50–80

Sex

ALL

Healthy volunteers

Accepted

You may be eligible if

For groups (AD with/ without DBS)
1. Confirmed Alzheimer's dementia diagnosis
2. Regular medications taking for at least 3 months
3. Clinical Dementia Rating: 0.5 - 2
4. Mini Mental Status Examination: ≦ 26
5. Amyloid PET: positive
6. Informed consent signed by patients or families
For normal control group
1. No cognitive impairment (Mini Mental Status Examination)
2. Amyloid PET: negative
3. Informed consent signed by patients and families

You may not be if

For groups (AD with/ without DBS)
1. Structural lesions identified by Magnetic resonance imaging (ex: stroke, brain surgery)
2. Other neurodegenerative/ neuropsychiatric diseases
3. Systemic medical diseases with cognitive impairment (ex: anemia, thyroid disease)
4. Can't have regular follow-up visit
For normal control group
1. Structural lesions identified by Magnetic resonance imaging (ex: stroke, brain surgery)
2. Dementia/ neurodegenerative/ neuropsychiatric diseases
3. Systemic medical diseases with cognitive impairment (ex: anemia, thyroid disease)
4. Can't have regular follow-up visit

The record

StatusUnknown

PhaseNot applicable

Taking part30

StartedApr 2020

UpdatedJul 17, 2020

Conditions

Alzheimer Disease Dementia, Alzheimer Type Deep Brain Stimulation

Where1

Buddhist Tzu Chi General Hospital
Hualien City, Taiwan