Study Evaluating the Safety and Efficacy of iR2 in Untreated and Unfit Elderly Patients With DLBCL

Exclusion Criteria

• •1. Has accepted Chemotherapy before
• •2. Uncontrollable cardio-cerebral vascular, coagulative, autoimmune, serious infectious disease
• •3. Lab at enrollment (Unless caused by lymphoma): Neutrophile\<1.5\*10\^9/L ;Platelet\<80\*10\^9/L; ALT or AST \>2\*ULN; AKP or bilirubin \>1.5\*ULN ;Creatinine\>1.5\*ULN
• •4. Not able to comply to the protocol for mental or other unknown reasons Pregnant or lactation
• •5. HIV infection
• •6. If HbsAg positive, should check HBV DNA, DNA positive patients cannot be enrolled. If HBsAg negative but HBcAb positive (whatever HBsAb status), should check HBV DNA,DNA positive patients cannot be enrolled.
• •7. Other uncontrollable medical condition that may that may interfere the participation of the study