SRAM study_Postate Cancer

Exclusion Criteria

• •Patients with active cancer other than prostate cancer and non-melanoma skin cancer.
• •Evidence of distant metastases
• •Regional lymph node involvement
• •Previous radical surgery (prostatectomy), cryosurgery, or HIFU for prostate cancer
• •Previous pelvic irradiation, prostate brachytherapy, or bilateral orchiectomy
• •Previous hormonal therapy, such as LHRH agonists (e.g., goserelin, leuprolide) or LHRH antagonists (e.g., degarelix), anti-androgens (e.g., flutamide, bicalutamide), estrogens (e.g. DES), or surgical castration (orchiectomy)
• •Unstable angina and/or congestive heart failure requiring hospitalization, transmural myocardial infarction within the last 6 months, acute bacterial or fungal infection requiring intravenous antibiotics, chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
• •Patients who have received prior chemotherapy.