The Effect of A-PRF+ Versus Open Flap Debridement in the Treatment of Patients With Stage III Periodontitis

Inclusion Criteria

• •Stage III periodontitis patient having at least one tooth with 2-wall, 3-wall, or combined 2- to 3-wall intraosseous defect ≥ 3 mm in depth (assessed by bone sounding, radiographic examination) with clinical attachment level (CAL) ≥ 5mm and pocket depth (PD) ≥ 6 mm.
• •Defect not extending to a root furcation area
• •Non-smokers.
• •No history of intake of medications affecting the periodontium in the previous 6 months.
• •Able to sign an informed consent form.
• •Patients age between 18 and 60 years old.
• •Patients who are cooperative, motivated, and hygiene conscious.
• •Systemically free according to Cornell Medical Index (Broadbent, 1951).