Age 20 through 40 years (inclusive) at screening, verified per site SOPs
Able and willing to provide written informed consent to be screened for and to take part in the study.
Able and willing to provide adequate locator information, as defined in site SOPs
Previously participated in the BONE: CARE study. Additional women will be recruited from the health centers where the BONE: CARE participants were receiving HIV care, and these will be matched to those from the BONE: CARE cohort based on age, duration on ART and contraception use.
Per participant report, plans to stay in the study catchment area in the next 24 months
Per participant report, willing to continue using similar contraceptive method as in the BONE: CARE study.
You may not be if
Currently pregnant/ breastfeeding or was pregnant/ breastfeeding in the last 6 months prior to screening
Intentions to get pregnant in the next two years
History of active tuberculosis
Pathologic bone fracture not related to trauma (ever)
Has pre-existing condition known to affect bone metabolism (e.g. thyrotoxicosis, tuberculosis, diabetes mellitus, liver or renal disease)
Is taking the following medications known to interfere with bone metabolism (steroids, anti-convulsants, bisphosphonates, cancer drugs, etc.).
