OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety and Effectiveness Evaluation

Exclusion Criteria

• •Patients will be excluded if ANY of the following conditions are present:
• •1. of age \< 21 years;
• •2. with echocardiographic measurements predicting SAM
• •1. LVEDD \< 45 mm
• •2. C-Sd \< 25mm (distance from the septum to the mitral valve coaptation point)
• •3. Basal-IVDd \> 15 mm
• •4. aorto-mitral angle \< 120°
• •5. pre-repair posterior leaflet height \> 15 mm
• •3. with cardiogenic shock;
• •4. with active endocarditis (or having had active endocarditis in the last three months);
• •5. with active myocarditis;
• •6. with heavily calcified mitral annulus;
• •7. with mitral stenosis;
• •8. unable to take anticoagulation medications;
• •9. with a known untreatable allergy to contrast media or nickel;
• •10. with a major or progressive non-cardiac disease that, in the investigator's experience, results in a life expectancy shorter than 1 year, or for whom the implant of the device produces an unacceptable increase of risk;
• •11. with contraindication to transoesophageal echocardiography;
• •12. with contraindication to cardiopulmonary bypass;
• •13. who are pregnant or breast-feeding women;
• •14. involved in any other clinical investigation for drugs or devices;
• •15. unable to understand and sign the ICF in absence of legal protection;
• •16. unable to read and write;