IGRT-schedule: 20 fractions to a total dose of 60 Gy
Personalized adaption of treatment plan dependning on volume-/ and constraint-thresholds and evaluation of biomarkers (multiparametric MRI, blood, tissue, stool, urine).
Treatment at MR-Linac allowed
Age
18–any
Sex
MALE
Healthy volunteers
Accepted
You may be eligible if
biopsy-proven prostate cancer with indication for RT
cT1b-cT3a cN0 cM0
ECOG Performance score 0-2
IPSS≤12 (before planning computed tomography i.e. reached after neoadjuvant androgen deprivation therapy or tamsulosin)
age\>18 years
Informed consent
contraindication against curative RT
age\<18 years
previous pelvic radiotherapy or planned pelvic radiotherapy
comorbidities interfering with image-guided radiotherapy
contraindications against multiparametric MRI (like hio prosthesis, pacer, allergy against contrast media)
prior transurethral resection, highly focussed ultrasound or other pre-treatment of prostate
