Diagnosis of manifest primary open angle glaucoma defined as pathological optic disc appearance
Glaucoma hemifield test outside normal limits
Untreated IOP ≥ 21 mmHg on at least three measurements in the medical history
Mean deviation in the visual field test is less than or equal 10dB (for one group) OR more than 10dB (for the other group)
Patients with normal tension glaucoma
Diagnosis of manifest normal tension glaucoma defined as pathological optic disc appearance
Glaucoma hemifield test outside normal limits
No evidence of untreated IOP \> 20 mmHg in the medical history
Mean deviation in the visual field is less than or equal 10dB (for one group) OR more than 10dB (for the other group)
Patients with ocular hypertension
Normal ophthalmic findings except presence of ocular hypertension defined as untreated IOP ≥ 21 mmHg on at least three measurements in the medical history
No signs of glaucomatous damage in the optic disc
or the glaucoma hemifield test
Healthy control subjects
Normal ophthalmic findings
IOP \< 20 mmHg on least three measurements
No evidence of increased IOP in the medical history
No signs of glaucomatous damage in the optic disc
or the glaucoma hemifield test
You may not be if
History of a severe medical condition as judged by the clinical investigator
Abuse of alcoholic beverages
Smoker
Participation in a clinical trial in the 3 weeks preceding the study
Exfoliation glaucoma, pigmentary glaucoma, history of acute angle closure
Intraocular surgery within the last 6 months
Ocular inflammation or infection within the last 3 months
