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COMPLETEDNANCT03870009

Validation of a Semi-automatized Method to Detect Cyclic Hyperinflation on CT-scan in ARDS

This study aims to validate a semi-automatized method to quantify cyclic hyperinflation on CT-scan of ARDS patients. The gold standard will be cyclic hyperinflation assessed on the same CT scan, usin...

Lead sponsor: Hospices Civils de Lyon•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Hospices Civils de Lyon

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•ARDS patients defined by the Berlin definition
•invasive mechanical ventilation with an arterial oxygen pressure (PaO2)/inspired fraction of oxygen (FiO2) ratio ≤ 200 mm Hg
•Indication of CT scan identified by the clinician in charge
•oesophageal catheter already inserted

Exclusion Criteria

•requirement of contrast agent for a chest CT-scan
•ARDS criteria present for more than 72 hours
•Chronic Obstructive Pulmonary Disease (COPD) on a previous lung function test
•pneumothorax or bronchopleural fistula
•patient without both sedation and neuromuscular blocking agents
•contra-indication to transport to the imaging facility
•treatment with extracorporeal membrane oxygenation or extracorporeal carbon dioxide (CO2) removal
•Latex or curare allergy
•patient previously included in the study
•pregnancy
•patient under limitation of care
•patient under an exclusion period following inclusion in another clinical trial
•patient under a legal protective measure
•patient unaffiliated with social security
•inform consent not obtained by next of kin

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: August 22, 2025Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment31

Start dateMay 2019

Last updatedAug 22, 2025

Condition

Acute Respiratory Distress Syndrome (ARDS)

Locations shown

Croix Rousse Hospital

Lyon

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: August 22, 2025Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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