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Computerized Cognitive Training in Young Adults With Depression | Clinical Trials | Clareo Health

TERMINATEDNA

Computerized Cognitive Training in Young Adults With Depression

Testing the Mechanism of Action of Computerized Cognitive Training in Young Adults With Depression: Clinical, Cognitive and Neuroimaging Outcomes

NCT03869463•Queens College, The City University of New York

View on ClinicalTrials.gov

Summary

The purpose of the study is to examine the benefits and mechanism of action of computerized cognitive training (CCT) on mood, neuropsychological deficits, everyday functioning, and brain activity among young adults with a range of depressive symptoms.

Eligibility

Age

18 - 29 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•1. Age 18-29.
•2. Current diagnosis of MDD/persistent depressive disorder or HDRS greater than or equal to 12. 3. Daily access to smartphone or tablet with internet connection for the study duration.
•4\. Willing and able to complete MRI, mood, and neuropsychological testing. 5. IQ \> 85.

Exclusion Criteria

•1. Lacks English-speaking ability as determined by self-report and clinical evaluation.
•2. Evidence of schizophrenia, schizoaffective disorder, psychosis, bipolar I and II disorder.
•3. Active suicidal ideation, intent, or plan, or past attempt within 1 year.
•4. Severe depression (HDRS \> 30).
•5. Neurological disorder (epilepsy, multiple sclerosis, traumatic brain injury, clinical stroke).
•6. Use of medications known to have negative impact on cognition (benzodiazepines and lorazepam equivalents \> 1mg daily, narcotics, anticholinergics).
•7. History of alcohol or drug abuse or dependence within past year.
•8. Acute, severe, unstable medical illness. For cancer, acutely ill patients (including those with metastases) are excluded, but past history of successfully treated cancer does not result in exclusion.
•9. Regular online brain training or regular player of non-fluency verbal games, defined as doing these procedures at a frequency of twice weekly or greater during the year prior to screening.

Locations (1)

Queens College

New York, New York, United States

Key Dates

Start Date

October 11, 2019

Primary Completion Date

March 31, 2023

Completion Date

March 31, 2023

Last Updated

September 25, 2023

Enrollment

ACTUAL participants

Conditions

Depressive Symptoms

Interventions

Computerized Cognitive Training

OTHER

Control

OTHER

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: September 25, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Computerized Cognitive Training in Young Adults With Depression

Inclusion Criteria

Exclusion Criteria

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