Computerized Cognitive Training in Young Adults With Depression

Exclusion Criteria

• •1. Lacks English-speaking ability as determined by self-report and clinical evaluation.
• •2. Evidence of schizophrenia, schizoaffective disorder, psychosis, bipolar I and II disorder.
• •3. Active suicidal ideation, intent, or plan, or past attempt within 1 year.
• •4. Severe depression (HDRS \> 30).
• •5. Neurological disorder (epilepsy, multiple sclerosis, traumatic brain injury, clinical stroke).
• •6. Use of medications known to have negative impact on cognition (benzodiazepines and lorazepam equivalents \> 1mg daily, narcotics, anticholinergics).
• •7. History of alcohol or drug abuse or dependence within past year.
• •8. Acute, severe, unstable medical illness. For cancer, acutely ill patients (including those with metastases) are excluded, but past history of successfully treated cancer does not result in exclusion.
• •9. Regular online brain training or regular player of non-fluency verbal games, defined as doing these procedures at a frequency of twice weekly or greater during the year prior to screening.