About Pricing FAQs Providers Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Back to clinical trial search

COMPLETEDNCT03860701

Remote Ischemic Conditioning in Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) affects up to 10% of very preterm infants. NEC mortality is high (30-50 %) and has remained unchanged over the last decades. New treatments are urgently needed. NEC pat...

Lead sponsor: The Hospital for Sick Children•1 locations•View source on ClinicalTrials.gov

Clareo plain-language summary

What this study is about

Generating AI summary...

Save this trial guide to your notes

Keep your clinical trial research organized — questions to ask, what to expect, and key details.

Sponsors

Lead Sponsor

The Hospital for Sick Children

Collaborators

Canadian Institutes of Health Research (CIHR)

An appropriately sized blood pressure cuff will be applied to an arm or leg and inflated to promote RIC. This study will be conducted in three phases to assess the feasibility and safety of RIC in relation to duration of ischemia time, number of cycles of RIC and whether it is feasible and safe to perform RIC on consecutive days.

Age

0 - 0 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Patients with NEC (stages I-III Bell's Classification)
•Weight greater or equal to 750 g.
•Gestational age \< 36 weeks.
•Patients whose parents consent to participate in the study.

Exclusion Criteria

•Patients with major congenital anomalies
•No antecedent of limb ischemia/limb thrombotic events.
•No antecedent diagnosis of occlusive arterial or venous thrombosis
•Hemodynamic instability

Related studies

Enrolling By Invitation

Do Probiotics Reduce The Risk Of Severe Necrotising Enterocolitis (NEC) In Infants Born Before 32 Weeks Gestation?

NCT06422988 · Enterocolitis, Necrotizing

Not Yet Recruiting

The Correlation Between Red Cell Transfusion and Complications of Prematurity

NCT07123948 · Retinopathy of Prematurity (ROP), Bronchopulmonary Dysplasia (BPD), and more

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

NCT01029353 · Infant, Newborn, Infant, Low Birth Weight, and more

Study of the Influence of Intraperitoneal Insufflation of CO2 by Laparoscopy on the Short-term Evolution of Premature Infants With Ulcerative Necrotizing Enterocolitis

NCT05882448 · Preterm Birth, Enterocolitis, Necrotizing

Role of Urinary Claudin-2, Caveolin-1, and EGF as Diagnostic Biomarkers of Necrotizing Enterocolitis in Preterm Neonates

NCT05335577 · Enterocolitis, Necrotizing, Infant, Premature

View all related studies →

Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: October 22, 2020Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment15

Start dateDec 2018

Last updatedOct 22, 2020

Condition

Enterocolitis, Necrotizing

Locations shown

The Hospital for Sick Children

Toronto, Ontario

For caregivers

Use Clareo to keep notes, questions, trial details, and next steps organized before and after appointments.

Start free trial →

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 22, 2020Data synced to Clareo: July 13, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions