Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Universitair Ziekenhuis Brussel
With
Vrije Universiteit Brussel
COPD is a heterogeneous disease, resulting in different phenotypes with varying clinical and pathophysiological characteristics. One of these pathophysiological features is chronic airway inflammation which can be eosinophilic of nature. Blood eosinophils could be an accessible biomarker for this eosinophilic inflammation.
Eosinophil counts can fluctuate due to their short half-life in blood and due to a diurnal rhythm. More needs to be known about this diurnal rhythm and the different confounding factors and sources of within-subject variability of this biomarker.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Patients willing and able to give informed consent for participation in the study.
Age 18 years or older.
Diagnosis of COPD according to GOLD (Global Initiative for Chronic Obstructive Lung Disease): post-bronchodilator Tiffeneau index \<0.7), in a stable state of the disease.
A smoking history of \>10 pack-years
You may not be if
Clinical diagnosis of asthma.
Use of systemic corticosteroids (oral, intravenous or infiltration) up to six weeks before inclusion.
