Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Henry Ford Health System
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patients who are recipients of allogeneic stem cell grafts.
2. Patients with the diagnosis of GVHD according to established criteria and physician decides to treat using ECP
3. Patient must have 100% chimerism with the donor
4. No recent donor lymphocyte infusion.
5. Patients must be able to sustain a platelet count and a hematocrit \> 20,000/mL and \> 27% respectively, with or without transfusions.
6. The absolute WBC must be \>1500/mL
7. Patient must be willing to comply with all study procedures.
You may not be if
1. Patients who are unable to tolerate the volume shifts associated with ECP treatment due to the presence of any of the following conditions: uncompensated congestive heart failure, pulmonary edema, severe asthma or chronic obstructive pulmonary disease, hepatorenal syndrome.
2. Active bleeding.
3. International normalized ration (INR) \>2.
4. Patients with known hypersensitivity or allergy to psoralen.
5. Patients with known hypersensitivity or allergy to both citrate and heparin.
6. Patients with co-existing photosensitive disease (e.g. porphyria, systemic lupus erythematosus, albinism) or coagulation disorders.
7. Active, uncontrolled infection
Clareo Health | Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis
